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MT-2 Melanotan Nouveaux Ltd


MT-2 (or Melanotan II) is another synthetic peptide of hormones nature and lactam cyclic analog of melanocortin protein hormone alpha-melanocyte stimulating hormone; its molecular weight/mass is 1024.2 with molecular formula is C50H69N15O9. This analog has typical features of proteins. MT-2 is a sterile, non-pyrogenic, white lyophilized powder intended for subcutaneous or intramuscular injection, after reconstitution with sterile Water for Injection (0,3% m-Cresol).

Mechanism of action

MT-II contributes to satiety via a hypothalamic signal. MT-II also affects skin pigmentation as it is a melanocyte-stimulating hormone (MSH). MT-II binds to melanocortin receptors and affects the MC4R activity demonstrating an effect on meal size and choice but not meal frequency.

In a pilot study using human subjects, a significant change in skin pigmentation (darkening) occurred after just 5 injections of MT-II used every other day. This same study also noted that males that used MT-II experienced penile erections concomitantly with “stretching and yawning.†Between one and five hours after injection of MT-II. Another study found 8 of 10 men increase erectile rigidity to 38 minutes verses 3 minutes with placebo. The only noted side effects were mild nausea, decreased appetite, and âœstretching and yawning.

Another potential benefit of MT-II is its affects on food choice, intake, and nutrient partitioning. Banno’s study surmised that food intake and body weight were decreased by chronic administration of MT-II. Insulin sensitivity as well as glucose tolerance was improved by MT-II. Serum triglyceride levels were also decreased by MT-II, and the affects persisted for at least 25 days. Thus one can conclude MT-II could be used to treat obesity, metabolic syndrome, and any co morbid disorders.

Adverse reaction

Facial Flushing
Injection site reactions
Zero incidence of erections

No change in vital signs or haematological parameters, blood biochemistry (liver and renal function)

Instructions for reconstitution

The injection is given into the sub-cutaneous layer which includes adipose tissue (fat).

If you are using insulin syringes which have short needles, you will need to enter the skin at 90°. to the skin, otherwise you can inject as shown in the illustration above with a 29 or 30 gauge, 0.5" needle.


Recommended dosage of MT-2: 0.25 - 1.5 mg once per day.


This product can be used not more than 3 years from the production date (see box).

After reconstitution, may be stored for maximum of 14 days in a refrigerator at 2°C – 8°C.

Store vials in an upright position.

Store in a refrigerator (2°C – 8°C). Keep in the outer carton in order to protect from light.

For one month can be stored at room temperature.

MT-2 Melanotan: 20 mg

MT-2 Melanotan Nouveaux

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